QS-Abrocitinib
1622902-68-4
C14h21n5o2s
N-M
Negotiable
Normal
>12 Months
Abrocitinib
Abrocitinib
>99%
Abrocitinib
PF-04965842(Abrocitinib)
White Powder
White
10.55±0.40
Pharmaceutical Grader
>99%
Pharmaceutica
COA
HPLC
474
C14h21n5o2s
323.42
1.36
99.4
QS-Abrocitinib
Negotiable
>99%
Xi`an
Product Description
Pharma CAS 1622902-68-4 Abrocitinib Powder Abrocitinib
Abrocitinib (PF-04965842, PF04965842), Also known as Abrotinib, it is an orally administered JAK1 selective inhibitor with an IC50 of 29 nM, which can be used for autoimmune diseases. The overexpression and mutation of JAK1 are closely related to the occurrence and development of tumors. The IC50 values of Abrotinib on JAK2/3 and TYK2 were 803 nM and> 10 μ M and 1.253 μ M.| Product name | Abrocitinib |
| Cas number | 1622902-68-4 |
| Appearance | White powder |
| MF | C14H21N5O2S |
| MW | 323.42 |
PF-04965842 (Abrotinib) has achieved positive results in multiple phase 3 clinical trials targeting patients with moderate to severe atopic dermatitis. It has shown statistically significant improvements in skin symptom clearance rate and disease severity, and rapidly improves itching symptoms in patients compared to placebo.
