Mirabegron is a pharmacological compound used for the treatment of overactive bladder (OAB). It is a selective β3-adrenergic receptor agon that stimulates the relaxation of the detrusor smooth muscle in the bladder, resulting in increased bladder capacity and reduced urinary urgency and frequency.
Function
Mirabegron's main function is to relax the smooth muscle of the bladder by activating β3-adrenergic receptors. This mechanism of action differs from traditional antimuscarinic agents commonly used to treat OAB. Mirabegron's selective action on β3-adrenergic receptors allows for increased bladder capacity without affecting other organs or causing systemic side effects.
Application
Mirabegron is primarily used in the treatment of overactive bladder (OAB) symptoms, such as urinary urgency, frequency, and incontinence. It offers an alternative to antimuscarinic medications for patients who are intolerant or unresponsive to conventional therapies. Mirabegron's efficacy in improving OAB symptoms has been documented in clinical trials and it has been approved by regulatory authorities for use in various countries. Its application in the field of urology has provided a valuable option for managing OAB and improving patient quality of life.
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