| Name | D-Camphorsulfonic acid |
| Synonyms | 2-Oxobornane-10-sulphonic acid; 1S-(+)-Camphor-10-sulfonic acid; D-2-Oxobornane-10-sulfonic acid; D-(+)-Camphor-10-sulfonic acid; D(+)-10-Camphorsulfonic acid; CSA |
| Molecular Structure | |
| Molecular Formula | C10H16O4S |
| Molecular Weight | 232.29 |
| CAS Registry Number | 3144-16-9 |
| EC Number | 221-554-1 |
| Melting point | 195 ºC |
|---|---|
| alpha | 22 º (589nm, c=20, H2O 25 ºC) |
| Water solubility | SOLUBLE |
D-Camphorsulfonic acid is a derivative of camphor sulfonic acid with the following properties:
1. Appearance: D-Camphorsulfonic acid is a white crystalline solid.
2. Solubility: D-Camphorsulfonic acid can dissolve in alcohol and ether solvents, but is almost insoluble in water.
The main uses of D-Camphorsulfonic acid are as follows:
1. Chiral reagent: D-Camphorsulfonic acid is often used as a catalyst and ligand for chiral compounds.
2. Chemical synthesis: D-Camphorsulfonic acid can catalyze important reactions such as asymmetric synthesis in organic synthesis reactions.
3. Splitting agent: D-Camphorsulfonic acid can be used as a splitting agent and a catalyst for dipeptide coupling.
Optically active left-handed and right-handed camphor sulfonic acid is an important chiral isomer drug resolving agent. The right-handed form can be obtained from natural camphor through bromination and sulfonation, or from racemic camphor sulfonic acid through induced crystallization separation.
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