VITAMIN B COMPLEX INJECTION
Indicatios:
In disorders requiring parenteral administration of vitamins, i.e. pre- and post-operative treatment, when requirements are increased as in fever, severe burns, increased metabolism, pregnancy, gastrointestinal disorders interfering with intake or absorption of vitamins, prolonged or wasting diseases, alcoholism and where other deficiencies exist.
Dosage and administration:
Administer by subcutaneous or intramuscular injection. High concentrations given intravenously may be diluted using parenteral infusion solutions.
Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever the solution and container permit.
Contraindications:
Sensitivity to the ingredients listed
Precautions:
The usual precautions for parenteral administration should be observed. Do not inject if precipitation occurs. Inject slowly by the intravenous route. High concentrations should be diluted using Normal Saline Injection when given intravenously.
Adverse reactions:
Mild transient diarrhea, polycythemia vera, peripheral vascular thrombosis, itching transitory exanthema, feeling of swelling of entire body, anaphylactic shock and death.
Sensitivity to the ingredients listed may occur.
Use should be discontinued upon observance of any untoward reaction.
Pain upon intramuscular injection may be noted.
Drug interactions:
Pyridoxine may increase the peripheral metabolism of levodopa, reducing therapeutic efficacy of the latter drug. Therefore, patients with Parkinson's disease who are receiving treatment with plain levodopa should not take vitamin B6 in doses which greatly exceed the daily requirement. This does not apply when levodopa is combined with a peripheral decarboxylase inhibitor.
Storage:
Store away from light and in a cool and dry place.
Do not permit to freeze.
