Trilostane
13647-35-3
13647-35-3
13647-35-3
Pharm&Food
Pharm&Food
MSDS, FDA, GMP
Pharm&Food
13647-35-3
Ordinary Goods Truck
White Powder
Recedar
Drum
99%
China
0000
Product Description
99% Veterinary use raw powder Trilostane with CAS 13647-35-3
Trilostane
Trilostane is an inhibitor of 3β-hydroxysteroid dehydrogenase used in the treatment of Cushing's syndrome and primary hyperaldosteronism. These are both disorders where excess amounts of corticosteroid hormones are produced in the body. Corticosteroids are essential for the body to make use of carbohydrates, fats and proteins and for a normal response to stress. They are also necessary for the regulation of salt and water balance in the body. Trilostane helps prevent the production of corticosteroids, controlling the symptoms associated with these disorders.
Trilostane can also be useful in the treatment of breast cancer that has relapsed in women who have gone through menopause.
Trilostane
CAS: 13647-35-3
MF: C20H27NO3
MW: 329.43
EINECS: 237-133-0
Melting point 264 °C
Boiling point 467.02°C (rough estimate)
solubility DMSO: ≥17mg/mL
form powder; color white to tan
Uses An inhibitor of steroid biosynthesis. Used as an adrenocortical suppressant. Used in the treatment of breast cancer
Trilostane is an inhibitor of 3β-hydroxysteroid dehydrogenase used in the treatment of Cushing's syndrome and primary hyperaldosteronism. These are both disorders where excess amounts of corticosteroid hormones are produced in the body. Corticosteroids are essential for the body to make use of carbohydrates, fats and proteins and for a normal response to stress. They are also necessary for the regulation of salt and water balance in the body. Trilostane helps prevent the production of corticosteroids, controlling the symptoms associated with these disorders.
Trilostane can also be useful in the treatment of breast cancer that has relapsed in women who have gone through menopause.
| Package | carton drum with two plastic bags inside |
| Net weight | 25KG/Drum |
| Storage | Sealed in cool and dry place to avoid moisture and light |
| Shelf life | 2 years when properly stored |
| Lead time | 1~3 days after confirmation |
| Test Items | Test Standard |
| Appearance | white or off- white powder |
| Identification | Positive |
| Solubility | Soluble in dimethyl sulfoxide and pyridine; slightly soluble in ethanol and water. |
| Melting point | 257°C to 270°C |
| Loss on Drying | ≤ 0.5% |
| Residue on ignition | ≤ 0.1% |
| Heavy metals | ≤20 ppm |
| Residual solvent | ≤0.5% |
| Related impurities | ≤ 1.0% |
| Specific rotation | +137° to +139°C |
| Single Impurity | ≤0.5% |
| HPLC purity | ≥99.0% |
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