| Product name | KP-1 |
| CAS no. | 936487-99-9 |
| Molecular Formula | C19H14FN2O+ |
| Molecular Weight | 305.33 |
| Brand Name | Senwayer |
KP1 is a peptide representing the sequence Phe57 to Lys86 of the anti aging protein Klotho, and is one of the buried β-strands in the N-terminal domain. KP1 mimics the anti-fibrotic action of Klotho by constraining TGF-β signaling, KP1 acts through binding to TGF-β receptor 2 (TβR2) and disrupting TGF-β/TβR2 interaction. KP1 inhibits multiple downstream TGF-β pathways including activation of Smad2/3 and mitogen activated protein kinases. In mouse models of renal fibrosis, KP1 preserves kidney function, ameliorates renal fibrosis and restores endogenous Klotho expression.
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1. Rich experience.
Our company is a professional production leading factory in China in pharmaceutical area of many years, our products have exported to Germany, Spain, UK, USA, Australia, Middle East, and so on other country, and we have got very good feedback from our customers, we had Established long friendly relations of cooperation.
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Good quality is one of our secret success, welcome order the samples, MOQ just 5 grams.
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We have special way could ship 0.01kg to 3.5kg products a time. We offer melting powder into liquid service. And ship the liquid in special bottles.
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