175481-36-4
175481-36-4
C13h18n2o3
605-756-0
Biochemical Reagents
For Biological Purpose
Standard
Diagnostic Reagents
Scientific Research, Health
Biochemical Reagent
175481-36-4
White
250.29
Powder
C13h18n2o3
ECHEMI
25kg/Package
1KG
China
Product Description
| Melting point | 141-143?C |
| alpha | D23 +16.0° (c = 1 in CH3OH) |
| Boiling point | 536.4±50.0 °C(Predicted) |
| density | 1.120±0.06 g/cm3(Predicted) |
| Fp | 2ºC |
| storage temp. | Refrigerator |
| solubility | DMF: 20 mg/ml; DMSO: 20 mg/ml; Ethanol: 20 mg/ml; PBS (pH 7.2): 2 mg/ml |
| form | A crystalline solid |
| pka | 14.19±0.46(Predicted) |
| InChI | InChI=1S/C13H18N2O3/c1-10(16)15-12(9-18-2)13(17)14-8-11-6-4-3-5-7-11/h3-7,12H,8-9H2,1-2H3,(H,14,17)(H,15,16)/t12-/m1/s1 |
| InChIKey | VPPJLAIAVCUEMN-GFCCVEGCSA-N |
| SMILES | C(NCC1=CC=CC=C1)(=O)[C@H](NC(C)=O)COC |
| CAS DataBase Reference | 175481-36-4 |
Lacosamide is an anticonvulsant and analgesic compound used for the treatment of partial-onset seizures and neuropathic pain. It can also used for the treatment of status epilepticus. Its analgesic effect is mediated by its inhibitory effect on sodium channels, which leads to neural membrane depolarization. Its interaction with the collapsin-response mediator protein 2 (CRMP-2 alias DRP-2) may also facilitate the above process, although the detailed mechanism remains to be elucidated.
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